FOLIRX

The science

A formula built on what the literature already knows.

Active 1

Minoxidil 6%

Opens follicular potassium channels and prolongs the anagen growth phase. Compounded above the OTC strength of 5%.

At 6%, the dose-response benefit over standard 5% is well documented. The trade-off is dryness — which is exactly why we pair it with a moisture-preserving carrier.

Strength
6%
Mechanism
K+ channel opener
Evidence
Decades of RCTs

Active 2

Finasteride 0.25%

Blocks DHT, the hormone responsible for male pattern hair loss. Topical delivery means systemic exposure is a fraction of the oral dose.

Topical finasteride dramatically reduces systemic absorption versus oral finasteride. This is the single biggest reason men hesitate on oral fin and shouldn't on topical.

Strength
0.25%
Mechanism
5α-reductase inhibitor
Evidence
Multiple topical RCTs

Active 3

Tretinoin 0.025%

A retinoid that increases scalp absorption of minoxidil up to 3x, so the formula does more with each dose.

Tretinoin's role here isn't cosmetic. It's an absorption enhancer — keratinizing scalp tissue is reorganized so minoxidil reaches the follicle in higher concentration.

Strength
0.025%
Mechanism
Retinoid
Evidence
Olsen et al. 1986

Why compounded

More than one molecule, more than one mechanism.

OTC minoxidil is a single drug at a fixed strength. FoliRx combines three actives at three different mechanisms in one carrier — that's the difference between fighting hair loss with one tool and fighting it with three.

Compounded at a 503A FDA-recognized pharmacy, every formula is built per-prescription. Strengths can be adjusted by your physician. Carriers can be swapped if your scalp is sensitive. That kind of personalization isn't possible with mass-market products.